Flat keloids, refer to those keloids that are not rising significantly above the skin level and do not forms keloid tumors or nodules in the skin. Cases of flat keloids are seen mostly among Asians, light colored individuals and Europeans. Individuals with dark color skin, Africans and African Americans can also have flat keloids.

We do not know why set of genetic factors result in a keloid to take flat form as opposed to become nodular. We can only assume that there must be different and unique set of genes that drive different types of keloids. Unfortunately, research in this area has been extremely limited and none of these genes have ever been discovered. Flat keloids are often treated with intralesional injection of steroids or chemotherapy drugs. Response rates to these treatments vary. In minority of patients, these keloids are very sensitive to steroid injections and may totally resolve after a few injections. In others, these keloids either do not respond to steroid injections, or have a short and temporary response, or can even get worse by the injections.

Flat keloids, often cause itching, pain, and local discomfort. These keloids can take on the form of dumbbell or butterfly. Surgery does not play a role in treatment of flat keloids. Indeed, surgery will make these keloids worse. Patients will grow a much bigger keloid at the site of surgery. Cryotherapy alone or in combination with chemotherapy may be the best option for treating these keloids.

Keloid is an area of unmet medical need. We need to discover better treatments for this condition.